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On Feb. 1, the Substance Abuse and Mental Health Services Administration (SAMHSA) issued a final rule that updates regulations for Opioid Treatment Programs (OTP) and the standards for treatment of opioid use disorder (OUD). The rule makes some COVID-19-related flexibilities permanent, including take-home doses of methadone, the ability of an OTP to prescribe medication for OUD via telehealth without an initial in-person physical evaluation, and the removal of certain requirements for admission to an OTP to better align with evidence-based practice. The rule also promotes patient-centered models of care that are aligned with management approaches for other chronic conditions. Additional details are available on the SAMHSA website.